细胞凋亡活体检测—艾美捷FLIVO探针活体凋亡检测工具

Apoptosis plays an important role in embryonic development, hematopoiesis, maturation of immune system, maintenance of cell stability and growth balance of normal tissues and organs, and even aging of the body. Therefore, the research on apoptosis has been widely carried out in clinical and basic fields, and the detection method of apoptotic cells is very important.

FLIVO ® (Fluorescent in vivo) is a powerful non-invasive method to detect the activity of caspase in vivo. NIR-FLIVO 690 tracer is a non cytotoxic, fluorescent inhibitor of caspases, which is optimized for use in the whole living animal. ICT's NIR-FLIVO 690 tracer probe contains the preferred binding sequence for most caspases (Val Ala Asp or VAD).

Next, let's talk about the ImmunoChemistry (ICT) FLIVO probe, which is used for in vivo detection of apoptosis, to help you with high-precision detection.

FLIVO是细胞渗透性,无毒的caspase抑制剂,可在体内检测caspase介导的活体动物凋亡。

艾美捷ImmunoChemistry（ICT）FLIVO探针系列天冬氨酸蛋白酶(Caspases)活性检测试剂盒，及 FLIVO示踪剂，主要用于细胞凋亡活体检测，助力科研。

FLIVO探针是什么？

FLIVO(FLuorescence in vIVO)探针是细胞渗透性、无毒性的天冬氨酸蛋白酶(Caspases)荧光抑制剂，FLIVO可以用于检测活体动物体内Caspase介导的细胞凋亡、焦亡。FLIVO非常敏感，自然发生的低水平细胞凋亡也会被检测到。  

艾美捷 FLIVO探针活体凋亡检测之FAM-FLIVO®体内Poly Caspase检测试剂盒：  

1. FAM FLIVO In vivo Poly Caspase Assay * * * Green carboxyl fluorescein (# 980, 6T; # 981, 24T)

Samples: living animals, isolated tissues

2. SR-FLIVO In vivo Poly Caspase Assay * * * Red sulfonylrhodamine B (# 982, 6T; # 983, 24T)

Samples: living animals, isolated tissues

艾美捷ICT FLIVO探针活体凋亡检测之FLIVO示踪剂：

9112  NIR-FLIVO 690 Tracer In vivo Assay ***Fluorescent label Dylight690 living animals and tissues in vitro 20T  

9113  NIR-FLIVO 690 Free Dye Control Assay ***Fluorescent label Dylight690 living animals and tissues in vitro 20T

9114  NIR-FLIVO 747 Tracer In vivo Assay ***Fluorescent label Dylight747 Living animals and tissues in vitro 20T

9115  NIR-FLIVO 747 Free Dye Control Assay***荧光标签Dylight747 Fluorescent label Dylight747 Living animals and tissues in vitro 20T  

* 仅供科研使用，不得用于医疗.

FLIVO探针的活体使用对药物测定研究很有价值，因为通过活体动物的荧光成像可测定药物反应性所引起的凋亡水平升高或降低。凋亡水平的升高使得粘附的探针更多，因此荧光强度增加。此外，活体技术避免了从动物上取出细胞和组织的需要，这会进一步诱导凋亡。

来源：https://www.amyjet.com/featured/in-vivo.shtml